Contact tracing shows no transmission from monkeypox index case – Consumer Health News

TUESDAY, Nov. 8, 2022 (HealthDay News) — No secondary cases were observed during an extensive contact investigation in response to the first case of monkeypox virus (MPXV) infection in the United States. The results of the survey were published online on November 8 in the Annals of Internal Medicine.

Erica S. Shenoy, MD, Ph.D., of Massachusetts General Hospital, Boston, and colleagues describe the contact tracing and exposure investigation of the index patient infected with MPXV, identified in May 2022 in the United States. United.

The researchers identified 37 community contacts and 129 healthcare contacts, of which four, 49 and 113 were at high, intermediate and low or uncertain risk, respectively. During the surveillance period, 15 healthcare contacts developed symptoms; three met the criteria for the MPXV test and all had negative results. Two of the community contacts developed symptoms, but did not meet criteria for MPXV testing and did not show disease progression consistent with monkeypox. Three of four high-risk exposed individuals who were offered post-exposure prophylaxis (PEP) elected to receive PEP. Two of 10 healthcare workers with intermediate risk exposures for whom PEP was offered as part of informed clinical decision-making elected to receive PEP. At the end of the 21-day surveillance period, no transmission was identified, despite the delay in recognition of monkeypox in the index patient.

“Public health authorities and health care institutions should consider how these results can inform revised exposure risk estimates, monitoring requirements, and recommendations for PEP,” the authors write.

Summary/Full text